When Dr. Marcus Sommers realizes that he and his troubled, estranged brother David may be prone a fatal brain disease that runs in their family, he decides to make peace with his sibling, and invites him on a trip to the Rockies. There, the brothers bond over their shared enthusiasm for cycling and decide to enter a grueling bike race through the mountains. However, Marcus' health soon begins to fail, and David must compete without his brother at his side.
Hardened criminal Maggie Hayward's consistent violence, even in police custody, ends in the execution chamber. However, top-secret US government agent 'Bob' arranges a staged death, so Maggie can be elaborately trained as a phantom killer and subdued into obedience.